The aim of this project is to develop novel malaria vector control tools that can be classified as ‘MCDs’ or ‘Mosquito Contamination Devices’. MCDs are devices that are attractive to mosquitoes and upon contact results in contamination and/or infection of the mosquitoes with insecticides.
There is a dire need for innovative malaria vector control tools that can be implemented at house level or in an area-wide fashion. Our goal is to develop MCDs that can be exploited as novel vector control products and effectively kill malaria mosquitoes. We aim for product innovations that move beyond personal protection and can exert a major additional impact on mosquito densities and malaria transmission intensity in resource-poor countries.
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This Consortium aims to develop low-tech attractive stations containing novel mosquito control agents that can be used in integrated vector management (IVM) strategies to complement indoor vector control tools and face the challenge of insecticide resistance.
Its objectives are:
to develop long-lasting applications of mosquito infectants and contaminants,
to design and test new (low-tech) prototype devices
to lure and contaminate malaria mosquitoes by incorporating attractive stimulants
to test and optimize device impacts under tropical field conditions
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Malaria infects 300 million people worldwide every year, causing a massive public health and economic burden in developing countries. Current malaria control relies heavily on chemical insecticide technologies, such as Insecticide Treated Nets (ITNs) and Indoor Residual Sprayings (IRS), targeting the adult mosquito vectors. However, resistance is rapidly building up against these chemical insecticides and novel control agents with new and effective modes of action are thus urgently needed. There is, therefore, a dire need for an innovative vector control approach.
Use of MCDs can help to move beyond personal protection and is expected to exert a major additional impact on mosquito densities. By developing an effective and low-cost MCD product that can be implemented in an Integrated Vector Management context we expect to:
1) Deliver a precision-targeted and easy to deploy mosquito control device that can be used in the peri-domestic domain and provide a low-cost vector control tool that enables the effective use of novel bioactives and can complement existing malaria interventions.
2) Provide a means for effective resistance management, by enabling the efficient use of alternative insecticides, resistance-breaking powder applications, and/or the use of multiple bioactives (in combination therapies, mosaics or rotations) to slow the evolution of resistance.
3) Achieve complementing and potentially synergistic impacts between our MCDs and current tools such as Indoor Residual Spraying (IRS) and Insecticide Treated bednets (ITNs); rendering these chemical strategies more effective and expanding their effective lifespan.